Scientist II- Protein Expression
Laboratory
South San Francisco, CA, US
Pay Rate Low: 48.00 | Pay Rate High: 52.00
- Added - 23/06/2025
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Our esteemed client, a trailblazing global pharmaceutical powerhouse, renowned for their expertise in developing and manufacturing a wide array of world-class pharmaceutical drugs, life-saving vaccines, and innovative animal-health products, is in search of a skilled Scientist II- Protein Expression to join their dynamic team in South San Francisco, CA!
Job type: 1 year contract
Pay rate: $48/ hr. -$52/ hr.
Location: South San Francisco, CA
Job Description:
We are seeking a skilled Scientist II- Protein Expression, to support recombinant protein production and characterization efforts for early discovery research. This role involves hands-on work in mammalian cell culture, transfection, small-scale expression, and protein purification using both traditional and high-throughput methods.
Responsibilities:
Maintain and propagate CHO cells in suspension culture
Perform transient and stable transfections (CHO, HEK293)
Express and purify proteins (e.g., monoclonal and bispecific antibodies, Fc-fusions) using bench-top and magnetic-bead methods
Execute fed-batch cultures in shake flasks, tube spins, and multi-well plates
Perform analytical QC: SDS-PAGE, HPLC/UPLC, UV-Vis, NanoDrop, CESDS
Track data and maintain documentation using ELNs and analytical tools
Support multiple projects in a fast-paced, collaborative lab environment
Qualifications:
B.S. in Biochemistry, Cell/Molecular Biology, Bioprocess Engineering, or related field + 3 years’ experience (or M.S. + 1 year)
Proficient in mammalian cell culture, aseptic technique, and protein expression
Basic experience in protein purification and analytical characterization
Strong organizational skills, attention to detail, and ability to multitask
Familiar with Vicell, metabolite analyzers, ELN, MS Office; experience with Dotmatics, Benchling, or Spotfire is a plus
*This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you! *
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We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.